Silly Queries for Beginners

I’m pretty sure this topic has come up countless times before, but I have a health query regarding cages.

What’s the general rule for determining if there’s any risk to your organ? I just got my hands on a CB-3000 and use it with the biggest stock ring paired with the smallest spacer. It’s been on continuously for roughly two and a half days, except when I briefly took it off to test out other rings or clean up once or twice daily (with permission from my key holder). Aside from some mild discomfort during erections and slight chafing that has since resolved, everything is fine even while sleeping. Honestly, it feels quite comfortable. Would you recommend leaving it down for longer stretches, like at night, or is continuous wear perfectly acceptable as long as there’s no swelling, circulation problems, or pain?